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Publications

Liquid Biopsy

Marino et al, Biochem Biophys Rep 2024

PIK3CA mutation analysis in circulating tumor cells of patients with hormone receptor positive metastatic breast cancer

Sementsov et al, EMBO Mol Med 2024

Mutation analysis in individual circulating tumor cells depicts intratumor heterogeneity in melanoma

Carniti et al, Blood Adv 2024

Monocytes in leukapheresis products affect the outcome of CD19-targeted CAR T-cell therapy in lymphoma patients

Kostler et al, Methods Mol Biol 2024

Circulating Tumor Cell Enrichment and Single-Cell Isolation Combining the CellSearch® and DEPArray™ Systems

Lessi et al, Int J Mol Sci 2023

Innovative Approach to Isolate and Characterize Glioblastoma Circulating Tumor Cells and Correlation with Tumor Mutational Status

Allsopp et al, Clin Chem 2023

A Rapid, Shallow Whole Genome Sequencing Workflow Applicable to Limiting Amounts of Cell-Free DNA

Rossi et al, Front Genet 2022

From phenotypical investigation to RNA-sequencing for gene expression analysis: A workflow for single and pooled rare cells

Lessi et al, Cells 2022

Single-Cell Molecular Characterization to Partition the Human Glioblastoma Tumor Microenvironment Genetic Background

Vismara et al, Clin Chem 2022

Single-Cell Phenotypic and Molecular Characterization of Circulating Tumor Cells Isolated from Cryopreserved Peripheral Blood Mononuclear Cells of Patients with Lung Cancer and Sarcoma

Silvestri et al, Sci Rep 2022

Copy number alterations analysis of primary tumor tissue and circulating tumor cells from patients with early-stage triple negative breast cancer
 

Da Col et al, Front Oncol 2022

Image Analysis of Circulating Tumor Cells and Leukocytes Predicts Survival and Metastatic Pattern in Breast Cancer Patients
 

Grüntkemeier et al, Breast Cancer 2022

Single HER2‑positive tumor cells are detected in initially HER2‑negative breast carcinomas using the DEPArray™–HER2‑FISH workflow

D'Amico et al, Cancers 2022

Single-Cells Isolation and Molecular Analysis: Focus on HER2-Low CTCs in Metastatic Breast Cancer

Philippron et al, PLoS One 2021

Evaluation of a marker independent isolation method for circulating tumor cells in esophageal adenocarcinoma

Fernandez-Garcia et al, Br J Cancer 2022

Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer

Rossi et al, cancers 2022

Dissecting Molecular Heterogeneity of Circulating Tumor Cells (CTCs) from Metastatic Breast Cancer Patients through Copy Number Aberration (CNA) and Single Nucleotide Variant (SNV) Single Cell Analysis

Felici et al, BMC Cancer 2022

Circulating tumor cells from melanoma patients show phenotypic plasticity and metastatic potential in xenograft NOD.CB17 mice

Rothè et al, NPJ Breast Cancer 2022

Interrogating breast cancer heterogeneity using single and pooled circulating tumor cell analysis

Vismara et al, Clin Chem 2022

Single-Cell Phenotypic and Molecular Characterization of Circulating Tumor Cells Isolated from Cryopreserved Peripheral Blood Mononuclear Cells of Patients with Lung Cancer and Sarcoma

Silvestri et al, Sci Rep 2022

Copy number alterations analysis of primary tumor tissue and circulating tumor cells from patients with early-stage triple negative breast cancer

Da Col et al, Front Oncol 2022

Image Analysis of Circulating Tumor Cells and Leukocytes Predicts Survival and Metastatic Pattern in Breast Cancer Patients

Grüntkemeier et al, Breast Cancer 2022

Single HER2‑positive tumor cells are detected in initially HER2‑negative breast carcinomas using the DEPArray™–HER2‑FISH workflow

D'Amico et al, Cancers 2022

Single-Cells Isolation and Molecular Analysis: Focus on HER2-Low CTCs in Metastatic Breast Cancer

Gallerani et al, Cancers 2021

CNA Profiling of Single CTCs in Locally Advanced Esophageal Cancer Patients during Therapy Highlights Unexplored Molecular Pathways

Cani et al, Mol Oncol 2021

Serial monitoring of genomic alterations in circulating tumor cells of ER-positive/HER2-negative advanced breast cancer: feasibility of precision oncology biomarker detection

Salmon C et al, Cancers 2021

Image-Based Identification and Genomic Analysis of Single Circulating Tumor Cells in High Grade Serous Ovarian Cancer Patients

Oulhen et al, NPJ Precis Oncol 2021

Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors

Lovero et al, Br J Cancer 2021

Correlation between targeted RNAseq signature of breast cancer CTCs and onset of bone-only metastases
 

Rossi et al, Front Med 2021

Case Report: Analysis of Circulating Tumor Cells in a Triple Negative Spindle-Cell Metaplastic Breast Cancer Patient

Childs et al, Endocr Relat Cancer 2021

Whole genome sequencing of single circulating tumor cells from neuroendocrine neoplasms

Laprovitera et al, Front Cell Dev Biol 2021

Genetic Characterization of Cancer of Unknown Primary Using Liquid Biopsy Approaches

Ortolan et al, ESMO Open 2021

Blood-based genomics of triple-negative breast cancer progression in patients treated with neoadjuvant chemotherapy

Salvianti et al, Br J Cancer 2021

Circulating tumour cells and cell-free DNA as a prognostic factor in metastatic colorectal cancer: the OMITERC prospective study

Galardi et al, Breast Cancer Res 2021

Circulating tumor cells and palbociclib treatment in patients with ER-positive, HER2-negative advanced breast cancer: results from a translational sub-study of the TREnd trial

Wang et al, Front Mol Biosci 2021

Applying Single-Cell Technology in Uveal Melanomas: Current Trends and Perspectives for Improving Uveal Melanoma Metastasis Surveillance and Tumor Profiling

Silvestri et al, Cancers 2021

Detection of Genomically Aberrant Cells within Circulating Tumor Microemboli (CTMs) Isolated from Early-Stage Breast Cancer Patients

Lam et al, Cancer Immunol Immunother 2021

CD30+OX40+ Treg is associated with improved overall survival in colorectal cancer

Rossi et al, Cancers 2020

Single-Cell NGS-Based Analysis of Copy Number Alterations Reveals New Insights in Circulating Tumor Cells Persistence in Early-Stage Breast Cancer

Cappelletti et al, Int J Mol Sci 2020

Analysis of Single Circulating Tumor Cells in Renal Cell Carcinoma Reveals Phenotypic Heterogeneity and Genomic Alterations Related to Progression

Schochter et al, Cancers 2020

53BP1 Accumulation in Circulating Tumor Cells Identifies Chemotherapy-Responsive Metastatic Breast Cancer Patients

Tucci et al, Ther Adv Med Oncol 2020

Dual-procedural separation of CTCs in cutaneous melanoma provides useful information for both molecular diagnosis and prognosis

Werner-Klein et al, Nat Commun 2020

Interleukin-6 trans-signaling is a candidate mechanism to drive progression of human DCCs during clinical latency

Reduzzi et al, Int J Cancer 2019

A novel circulating tumor cell subpopulation for treatment monitoring and molecular characterization in biliary tract cancer

Chemi et al, Nat Med 2019

Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse

De Laere et al, Clin Cancer Res 2018

TP53 outperforms other androgen receptor biomarkers to predict abiraterone or enzalutamide outcome in metastatic castration-resistant prostate cancer

Paoletti et al, Cancer Res 2017

Comprehensive mutation and copy number profiling in archived circulating breast cancer tumor cells documents heterogeneous resistance mechanisms

Mesquita et al, Mol Oncol 2017

Molecular analysis of single circulating tumour cells following long-term storage of clinical samples

Bingham C et al, Breast Cancer Res Treat 2017

Mutational studies on single circulating tumor clles isolated form the blood of inflammatory breast cancer patients

Carter L et al, Nat Med 2016

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemo sensitive and chemo refractory small-cell lung cancer

Rothwell G et al, Mol Oncol 2015

Genetic profiling of tumours using both circulating free DNA and circulating tumour cells isolated from the same preserved whole blood sample

Vishnoi M et al, Sci Rep 2015

The isolation and characterization of CTC subsets related to breast cancer dormancy

Hodgkinson C.L.et al, Nat Med 2014

Tumorigenicity and genetic profiling of Circulating Tumor Cells in Small Cell Lung Cancer

Polzer B et al, EMBO Mol Med 2014

Molecular profiling of single circulating tumor cells with diagnostic intention

Peeters DJE, et al. Br J Cancer 2013

Semiautomated isolation and molecular characterization of single or highly purified tumour cells from CellSearch enriched blood samples using dielectrophoretic cell sorting

Fabbri F, et al. Cancer Lett 2013

Detection and recovery of circulating colon cancer cells using a dielectrophoresis-based device: KRAS mutation status in pure CTCs